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Cytokine-Induced Loss of Glucocorticoid Function: Effect of Kinase Inhibitors, Long-Acting β2-Adrenoceptor Agonist and Glucocorticoid Receptor Ligands
Acting on the glucocorticoid receptor (NR3C1), glucocorticoids are widely used to treat inflammatory diseases. However, glucocorticoid resistance often leads to suboptimal asthma control. Since glucocorticoid-induced gene expression contributes to glucocorticoid activity, the aim of this study was t...
Autores principales: | Rider, Christopher F., Shah, Suharsh, Miller-Larsson, Anna, Giembycz, Mark A., Newton, Robert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308083/ https://www.ncbi.nlm.nih.gov/pubmed/25625944 http://dx.doi.org/10.1371/journal.pone.0116773 |
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