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Monitoring Low Molecular Weight Heparins at Therapeutic Levels: Dose-Responses of, and Correlations and Differences between aPTT, Anti-Factor Xa and Thrombin Generation Assays
BACKGROUND: Low molecular weight heparins (LMWH’s) are used to prevent and treat thrombosis. Tests for monitoring LMWH’s include anti-factor Xa (anti-FXa), activated partial thromboplastin time (aPTT) and thrombin generation. Anti-FXa is the current gold standard despite LMWH’s varying affinities fo...
Autores principales: | Thomas, Owain, Lybeck, Emanuel, Strandberg, Karin, Tynngård, Nahreen, Schött, Ulf |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308107/ https://www.ncbi.nlm.nih.gov/pubmed/25625201 http://dx.doi.org/10.1371/journal.pone.0116835 |
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