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Novel codon-optimized mini-intronic plasmid for efficient, inexpensive, and xeno-free induction of pluripotency

The development of human induced pluripotent stem cell (iPSC) technology has revolutionized the regenerative medicine field. This technology provides a powerful tool for disease modeling and drug screening approaches. To circumvent the risk of random integration into the host genome caused by retrov...

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Detalles Bibliográficos
Autores principales: Diecke, Sebastian, Lu, Jiamiao, Lee, Jaecheol, Termglinchan, Vittavat, Kooreman, Nigel G., Burridge, Paul W., Ebert, Antje D., Churko, Jared M., Sharma, Arun, Kay, Mark A., Wu, Joseph C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308704/
https://www.ncbi.nlm.nih.gov/pubmed/25628230
http://dx.doi.org/10.1038/srep08081

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