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Identification of Fumarate Hydratase Inhibitors with Nutrient-Dependent Cytotoxicity
[Image: see text] Development of cell-permeable small molecules that target enzymes involved in energy metabolism remains important yet challenging. We describe here the discovery of a new class of compounds with a nutrient-dependent cytotoxicity profile that arises from pharmacological inhibition o...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308746/ https://www.ncbi.nlm.nih.gov/pubmed/25469852 http://dx.doi.org/10.1021/ja5101257 |