Cargando…

Effect of p62 on tau hyperphosphorylation in a rat model of Alzheimer's disease☆

Tau hyperphosphorylation is a main cause of neuronal loss in Alzheimer's disease, which can be caused by many factors, including oxidative stress. The multifunctional protein p62, which exists in neurofibrillary tangles and causes aggregation of hyperphosphorylated tau, not only serves as a rec...

Descripción completa

Detalles Bibliográficos
Autores principales: Zheng, Xianhong, Wang, Weiwei, Liu, Ruizhi, Huang, Honglan, Zhang, Rihui, Sun, Liankun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308800/
https://www.ncbi.nlm.nih.gov/pubmed/25657660
http://dx.doi.org/10.3969/j.issn.1673-5374.2012.17.004