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Higher gene expression variability in the more aggressive subtype of chronic lymphocytic leukemia

BACKGROUND: Chronic lymphocytic leukemia (CLL) presents two subtypes which have drastically different clinical outcomes, IgVH mutated (M-CLL) and IgVH unmutated (U-CLL). So far, these two subtypes are not associated to clear differences in gene expression profiles. Interestingly, recent results have...

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Detalles Bibliográficos
Autores principales: Ecker, Simone, Pancaldi, Vera, Rico, Daniel, Valencia, Alfonso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308895/
https://www.ncbi.nlm.nih.gov/pubmed/25632304
http://dx.doi.org/10.1186/s13073-014-0125-z