Cargando…

Higher gene expression variability in the more aggressive subtype of chronic lymphocytic leukemia

BACKGROUND: Chronic lymphocytic leukemia (CLL) presents two subtypes which have drastically different clinical outcomes, IgVH mutated (M-CLL) and IgVH unmutated (U-CLL). So far, these two subtypes are not associated to clear differences in gene expression profiles. Interestingly, recent results have...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ecker, Simone, Pancaldi, Vera, Rico, Daniel, Valencia, Alfonso
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308895/ https://www.ncbi.nlm.nih.gov/pubmed/25632304 http://dx.doi.org/10.1186/s13073-014-0125-z

Ejemplares similares

Aggressive chronic lymphocytic leukemia masked by extensive marrow fibrosis
por: Farooq, Hareem, et al.
Publicado: (2023)

An agent-based model of monocyte differentiation into tumour-associated macrophages in chronic lymphocytic leukemia
por: Verstraete, Nina, et al.
Publicado: (2023)

Aspartic Aminopeptidase Is a Novel Biomarker of Aggressive Chronic Lymphocytic Leukemia
por: Kakodkar, Pramath, et al.
Publicado: (2020)

Distinct Activities of Glycolytic Enzymes Identify Chronic Lymphocytic Leukemia Patients with a more Aggressive Course and Resistance to Chemo-Immunotherapy
por: Gdynia, Georg, et al.
Publicado: (2018)

Immune Checkpoint Pathway Expression in Lymphocyte Subpopulations in Patients with Common Variable Immunodeficiency and Chronic Lymphocytic Leukemia
por: Mertowska, Paulina, et al.
Publicado: (2023)

Upregulation of long noncoding RNA MIAT in aggressive form of chronic lymphocytic leukemias
por: Sattari, Arash, et al.
Publicado: (2016)

Two mouse models reveal an actionable PARP1 dependence in aggressive chronic lymphocytic leukemia
por: Knittel, Gero, et al.
Publicado: (2017)

Evaluation of prognostic variables in chronic lymphocytic leukemia and association with disease stage
por: Attia, Hanaa R.M., et al.
Publicado: (2021)

Chromatin network markers of leukemia
por: Malod-Dognin, N, et al.
Publicado: (2020)

TACI Expression and Signaling in Chronic Lymphocytic Leukemia
por: Mamara, Antigoni, et al.
Publicado: (2015)

First Case of Transformation of Immunoglobulin Heavy Chain Variable-Mutated Chronic Lymphocytic Leukemia Into Chronic Myeloid Leukemia
por: Zhang, Xueya, et al.
Publicado: (2019)

Concomitant heterochromatinisation and down-regulation of gene expression unveils epigenetic silencing of RELB in an aggressive subset of chronic lymphocytic leukemia in males
por: Marteau, Jean-Brice, et al.
Publicado: (2010)

Diagnosis and treatment of chronic lymphocytic leukemia: recommendations from the Brazilian Group of Chronic Lymphocytic Leukemia
por: Rodrigues, Celso Arrais, et al.
Publicado: (2016)

The histone methyltransferase EZH2 as a novel prosurvival factor in clinically aggressive chronic lymphocytic leukemia
por: Papakonstantinou, Nikos, et al.
Publicado: (2016)

Chronic Lymphocytic Leukemia
por: Vaisitti, Tiziana, et al.
Publicado: (2020)

Chronic lymphocytic leukemia
por: Rossi, Davide
Publicado: (2018)

High-risk subtypes of chronic lymphocytic leukemia are detectable as early as 16 years prior to diagnosis
por: Kolijn, P. Martijn, et al.
Publicado: (2022)

Aggressive NK-cell leukemia: clinical subtypes, molecular features, and treatment outcomes
por: Tang, Y-T, et al.
Publicado: (2017)

Automatic identification of informative regions with epigenomic changes associated to hematopoiesis
por: Carrillo-de-Santa-Pau, Enrique, et al.
Publicado: (2017)

A Challenging Case of Pseudohyperkalemia in Chronic Lymphocytic Leukemia
por: Alhaj Moustafa, Muhamad, et al.
Publicado: (2017)

Transformation of Canine Lymphoma/Leukemia to More Aggressive Diseases: Anecdotes or Reality?
por: Comazzi, Stefano, et al.
Publicado: (2015)

Transcriptome characterization by RNA sequencing identifies a major molecular and clinical subdivision in chronic lymphocytic leukemia
por: Ferreira, Pedro G., et al.
Publicado: (2014)

Low LEF1 expression is a biomarker of early T-cell precursor, an aggressive subtype of T-cell lymphoblastic leukemia
por: Wang, Mei, et al.
Publicado: (2020)

Low-depth whole genome sequencing reveals copy number variations associated with higher pathologic grading and more aggressive subtypes of lung non-mucinous adenocarcinoma
por: Wang, Zheng, et al.
Publicado: (2020)

Infrequent normal B lymphocytes express features of B-chronic lymphocytic leukemia
Publicado: (1982)

Transcriptomics-based validation of the relatedness of heterogeneous nuclear ribonucleoproteins to chronic lymphocytic leukemia as potential biomarkers of the disease aggressiveness
por: Alsagaby, Suliman A.
Publicado: (2019)

Decreased deformability of lymphocytes in chronic lymphocytic leukemia
por: Zheng, Yi, et al.
Publicado: (2015)

Variability within the human TERT gene, telomere length and predisposition to chronic lymphocytic leukemia
por: Wysoczanska, Barbara, et al.
Publicado: (2019)

Integrating epigenomic data and 3D genomic structure with a new measure of chromatin assortativity
por: Pancaldi, Vera, et al.
Publicado: (2016)

A six gene expression signature defines aggressive subtypes and predicts outcome in childhood and adult acute lymphoblastic leukemia
por: Wang, Jin, et al.
Publicado: (2015)

Alemtuzumab in chronic lymphocytic leukemia
por: Fraser, G., et al.
Publicado: (2007)

Lenalidomide and Chronic Lymphocytic Leukemia
por: González-Rodríguez, Ana Pilar, et al.
Publicado: (2013)

Chronic Lymphocytic Leukemia and Myelofibrosis
por: Darawshy, Fares, et al.
Publicado: (2018)

Leukostasis in Chronic Lymphocytic Leukemia
por: Singh, Navdeep, et al.
Publicado: (2020)

Chronic lymphocytic leukemia in China
por: Gale, Robert Peter
Publicado: (2022)

Pseudohyperkalemia in chronic lymphocytic leukemia
por: Gudgeon, Patrick, et al.
Publicado: (2023)

Genome-wide analysis of differential transcriptional and epigenetic variability across human immune cell types
por: Ecker, Simone, et al.
Publicado: (2017)

Acute Lymphoid Leukemia Cells with Greater Stem Cell Antigen-1 (Ly6a/Sca-1) Expression Exhibit Higher Levels of Metalloproteinase Activity and Are More Aggressive In Vivo
por: Hsu, Yu-Chiao, et al.
Publicado: (2014)

Predominant VH1-69 IgBCR Clones Show Higher Expression of CD5 in Heterogeneous Chronic Lymphocytic Leukemia Populations
por: Maisano, Domenico, et al.
Publicado: (2021)

Functional loss of IκBε leads to NF-κB deregulation in aggressive chronic lymphocytic leukemia
por: Mansouri, Larry, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_1b8iemj568a71ir5q9t1785jko