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TET proteins and the control of cytosine demethylation in cancer

The discovery that ten-eleven translocation (TET) proteins are α-ketoglutarate-dependent dioxygenases involved in the conversion of 5-methylcytosines (5-mC) to 5-hydroxymethylcytosine (5-hmC), 5-formylcytosine and 5-carboxycytosine has revealed new pathways in the cytosine methylation and demethylat...

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Detalles Bibliográficos
Autores principales:	Scourzic, Laurianne, Mouly, Enguerran, Bernard, Olivier A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308928/ https://www.ncbi.nlm.nih.gov/pubmed/25632305 http://dx.doi.org/10.1186/s13073-015-0134-6

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