Cargando…
Chemokine-mediated inflammation in the degenerating retina is coordinated by Müller cells, activated microglia, and retinal pigment epithelium
BACKGROUND: Monocyte infiltration is involved in the pathogenesis of many retinal degenerative conditions. This process traditionally depends on local expression of chemokines, though the roles of many of these in the degenerating retina are unclear. Here, we investigate expression and in situ local...
Autores principales: | Rutar, Matt, Natoli, Riccardo, Chia, RX, Valter, Krisztina, Provis, Jan M |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308937/ https://www.ncbi.nlm.nih.gov/pubmed/25595590 http://dx.doi.org/10.1186/s12974-014-0224-1 |
Ejemplares similares
-
Microglia-derived IL-1β promotes chemokine expression by Müller cells and RPE in focal retinal degeneration
por: Natoli, Riccardo, et al.
Publicado: (2017) -
Synthesis and Propagation of Complement C3 by Microglia/Monocytes in the Aging Retina
por: Rutar, Matt, et al.
Publicado: (2014) -
The broad-spectrum chemokine inhibitor NR58-3.14.3 modulates macrophage-mediated inflammation in the diseased retina
por: Fernando, Nilisha, et al.
Publicado: (2016) -
Small interfering RNA-mediated suppression of Ccl2 in Müller cells attenuates microglial recruitment and photoreceptor death following retinal degeneration
por: Rutar, Matt, et al.
Publicado: (2012) -
670 nm light mitigates oxygen-induced degeneration in C57BL/6J mouse retina
por: Albarracin, Rizalyn, et al.
Publicado: (2013)