Phosphorylation of Shox2 Is Required for Its Function to Control Sinoatrial Node Formation

BACKGROUND: Inactivation of Shox2, a member of the short‐stature homeobox gene family, leads to defective development of multiple organs and embryonic lethality as a result of cardiovascular defects, including bradycardia and severe hypoplastic sinoatrial node (SAN) and sinus valves, in mice. It has...

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Detalles Bibliográficos
Autores principales: Liu, Hongbing, Chen, Chao‐Hui, Ye, Wenduo, Espinoza‐Lewis, Ramón A., Hu, Xuefeng, Zhang, Yanding, Chen, YiPing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309068/
https://www.ncbi.nlm.nih.gov/pubmed/24847033
http://dx.doi.org/10.1161/JAHA.114.000796

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