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Cyclooxygenases 1 and 2 Differentially Regulate Blood Pressure and Cerebrovascular Responses to Acute and Chronic Intermittent Hypoxia: Implications for Sleep Apnea

BACKGROUND: Obstructive sleep apnea (OSA) is associated with increased risk of cardiovascular and cerebrovascular disease resulting from intermittent hypoxia (IH)‐induced inflammation. Cyclooxygenase (COX)‐formed prostanoids mediate the inflammatory response, and regulate blood pressure and cerebral...

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Detalles Bibliográficos
Autores principales:	Beaudin, Andrew E., Pun, Matiram, Yang, Christina, Nicholl, David D. M., Steinback, Craig D., Slater, Donna M., Wynne‐Edwards, Katherine E., Hanly, Patrick J., Ahmed, Sofia B., Poulin, Marc J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2014
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309085/ https://www.ncbi.nlm.nih.gov/pubmed/24815497 http://dx.doi.org/10.1161/JAHA.114.000875

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