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Hospital Variation in Survival Trends for In‐hospital Cardiac Arrest

BACKGROUND: During the past decade, survival after in‐hospital cardiac arrest has improved markedly. It remains unknown whether the improvement in survival has occurred uniformly at all hospitals or was driven by large improvements at only a few hospitals. METHODS AND RESULTS: We identified 93 342 a...

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Autores principales: Girotra, Saket, Cram, Peter, Spertus, John A., Nallamothu, Brahmajee K., Li, Yan, Jones, Philip G., Chan, Paul S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309112/
https://www.ncbi.nlm.nih.gov/pubmed/24922627
http://dx.doi.org/10.1161/JAHA.114.000871
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author Girotra, Saket
Cram, Peter
Spertus, John A.
Nallamothu, Brahmajee K.
Li, Yan
Jones, Philip G.
Chan, Paul S.
author_facet Girotra, Saket
Cram, Peter
Spertus, John A.
Nallamothu, Brahmajee K.
Li, Yan
Jones, Philip G.
Chan, Paul S.
author_sort Girotra, Saket
collection PubMed
description BACKGROUND: During the past decade, survival after in‐hospital cardiac arrest has improved markedly. It remains unknown whether the improvement in survival has occurred uniformly at all hospitals or was driven by large improvements at only a few hospitals. METHODS AND RESULTS: We identified 93 342 adults with an in‐hospital cardiac arrest at 231 hospitals in the Get With The Guidelines(®)‐Resuscitation registry during 2000–2010. Using hierarchical regression models, we evaluated hospital‐level trends in survival to discharge. Mean age was 66 years, 59% were men, and 21% were black. Between 2000 and 2010, there was a significant decrease in age, prevalence of heart failure and myocardial infarction, and cardiac arrests due to shockable rhythms (P<0.001 for all) and an increase in prevalence of sepsis, respiratory insufficiency, renal insufficiency, intensive care unit location, and mechanical ventilation before arrest (P<0.001 for all). After adjustment for temporal trends in baseline characteristics, hospital rates of in‐hospital cardiac arrest survival improved by 7% per year (odds ratio [OR] 1.07, 95% CI 1.06 to 1.08, P<0.001). Improvement in survival varied markedly and ranged from 3% in the bottom hospital quartile to 11% in the top hospital quartile. Compared with minor teaching hospitals (OR 1.04, 95% CI 1.02 to 1.06), hospital rate of survival improvement was greater at major teaching (OR 1.08, 95% CI 1.06 to 1.10) and nonteaching hospitals (OR 1.07, 95% CI 1.05 to 1.09, P value for interaction=0.03). CONCLUSION: Although in‐hospital cardiac arrest survival has improved during the past decade, the magnitude of improvement varied across hospitals. Future studies are needed to identify hospital processes that have led to the largest improvement in survival.
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spelling pubmed-43091122015-01-28 Hospital Variation in Survival Trends for In‐hospital Cardiac Arrest Girotra, Saket Cram, Peter Spertus, John A. Nallamothu, Brahmajee K. Li, Yan Jones, Philip G. Chan, Paul S. J Am Heart Assoc Original Research BACKGROUND: During the past decade, survival after in‐hospital cardiac arrest has improved markedly. It remains unknown whether the improvement in survival has occurred uniformly at all hospitals or was driven by large improvements at only a few hospitals. METHODS AND RESULTS: We identified 93 342 adults with an in‐hospital cardiac arrest at 231 hospitals in the Get With The Guidelines(®)‐Resuscitation registry during 2000–2010. Using hierarchical regression models, we evaluated hospital‐level trends in survival to discharge. Mean age was 66 years, 59% were men, and 21% were black. Between 2000 and 2010, there was a significant decrease in age, prevalence of heart failure and myocardial infarction, and cardiac arrests due to shockable rhythms (P<0.001 for all) and an increase in prevalence of sepsis, respiratory insufficiency, renal insufficiency, intensive care unit location, and mechanical ventilation before arrest (P<0.001 for all). After adjustment for temporal trends in baseline characteristics, hospital rates of in‐hospital cardiac arrest survival improved by 7% per year (odds ratio [OR] 1.07, 95% CI 1.06 to 1.08, P<0.001). Improvement in survival varied markedly and ranged from 3% in the bottom hospital quartile to 11% in the top hospital quartile. Compared with minor teaching hospitals (OR 1.04, 95% CI 1.02 to 1.06), hospital rate of survival improvement was greater at major teaching (OR 1.08, 95% CI 1.06 to 1.10) and nonteaching hospitals (OR 1.07, 95% CI 1.05 to 1.09, P value for interaction=0.03). CONCLUSION: Although in‐hospital cardiac arrest survival has improved during the past decade, the magnitude of improvement varied across hospitals. Future studies are needed to identify hospital processes that have led to the largest improvement in survival. Blackwell Publishing Ltd 2014-06-10 /pmc/articles/PMC4309112/ /pubmed/24922627 http://dx.doi.org/10.1161/JAHA.114.000871 Text en © 2014 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley Blackwell. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial (http://creativecommons.org/licenses/by-nc/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Original Research
Girotra, Saket
Cram, Peter
Spertus, John A.
Nallamothu, Brahmajee K.
Li, Yan
Jones, Philip G.
Chan, Paul S.
Hospital Variation in Survival Trends for In‐hospital Cardiac Arrest
title Hospital Variation in Survival Trends for In‐hospital Cardiac Arrest
title_full Hospital Variation in Survival Trends for In‐hospital Cardiac Arrest
title_fullStr Hospital Variation in Survival Trends for In‐hospital Cardiac Arrest
title_full_unstemmed Hospital Variation in Survival Trends for In‐hospital Cardiac Arrest
title_short Hospital Variation in Survival Trends for In‐hospital Cardiac Arrest
title_sort hospital variation in survival trends for in‐hospital cardiac arrest
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309112/
https://www.ncbi.nlm.nih.gov/pubmed/24922627
http://dx.doi.org/10.1161/JAHA.114.000871
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