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Preoperative low-dose ketamine has no preemptive analgesic effect in opioid-naïve patients undergoing colon surgery when nitrous oxide is used - a randomized study

Background: The analgesic properties of ketamine are associated with its non-competitive antagonism of the N-methyl-D-aspartate receptor; these receptors exhibit an excitatory function on pain transmission and this binding seems to inhibit or reverse the central sensitization of pain. In the literat...

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Detalles Bibliográficos
Autores principales: Nistal-Nuño, Beatriz, Freire-Vila, Enrique, Castro-Seoane, Francisco, Camba-Rodriguez, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309164/
https://www.ncbi.nlm.nih.gov/pubmed/25671084
http://dx.doi.org/10.12688/f1000research.5258.1