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Frequent Disruption of Chromodomain Helicase DNA-Binding Protein 8 (CHD8) and Functionally Associated Chromatin Regulators in Prostate Cancer

Abnormal expression and function of chromatin regulators results in the altered chromatin structure seen in cancer. The chromatin regulator CTCF, its cofactor CHD8, and antagonistic paralogue BORIS have wide-ranging effects on gene regulation. Their concurrent expression and regulation was examined...

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Detalles Bibliográficos
Autores principales:	Damaschke, Nathan A., Yang, Bing, Blute, Michael L., Lin, Chee Paul, Huang, Wei, Jarrard, David F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Neoplasia Press 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309256/ https://www.ncbi.nlm.nih.gov/pubmed/25499215 http://dx.doi.org/10.1016/j.neo.2014.10.003

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