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Cytoplasmic TAF2–TAF8–TAF10 complex provides evidence for nuclear holo–TFIID assembly from preformed submodules

General transcription factor TFIID is a cornerstone of RNA polymerase II transcription initiation in eukaryotic cells. How human TFIID—a megadalton-sized multiprotein complex composed of the TATA-binding protein (TBP) and 13 TBP-associated factors (TAFs)—assembles into a functional transcription fac...

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Detalles Bibliográficos
Autores principales: Trowitzsch, Simon, Viola, Cristina, Scheer, Elisabeth, Conic, Sascha, Chavant, Virginie, Fournier, Marjorie, Papai, Gabor, Ebong, Ima-Obong, Schaffitzel, Christiane, Zou, Juan, Haffke, Matthias, Rappsilber, Juri, Robinson, Carol V., Schultz, Patrick, Tora, Laszlo, Berger, Imre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309443/
https://www.ncbi.nlm.nih.gov/pubmed/25586196
http://dx.doi.org/10.1038/ncomms7011