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A Neuron-Specific Deletion of the MicroRNA-Processing Enzyme DICER Induces Severe but Transient Obesity in Mice
MicroRNAs (miRNAs) are small, non-coding RNA molecules that regulate gene expression post-transcriptionally. MiRNAs are implicated in various biological processes associated with obesity, including adipocyte differentiation and lipid metabolism. We used a neuronal-specific inhibition of miRNA matura...
Autores principales: | Mang, Géraldine M., Pradervand, Sylvain, Du, Ngoc-Hien, Arpat, Alaaddin Bulak, Preitner, Frédéric, Wigger, Leonore, Gatfield, David, Franken, Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309537/ https://www.ncbi.nlm.nih.gov/pubmed/25629159 http://dx.doi.org/10.1371/journal.pone.0116760 |
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