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Application of the C3-Binding Motif of Streptococcal Pyrogenic Exotoxin B to Protect Mice from Invasive Group A Streptococcal Infection
Group A streptococcus (GAS) is an important human pathogen that produces several extracellular exotoxins to facilitate invasion and infection. Streptococcal pyrogenic exotoxin B (SPE B) has been demonstrated to be an important virulence factor of GAS. Our previous studies indicate that SPE B cleaves...
Autores principales: | Kuo, Chih-Feng, Tsao, Nina, Cheng, Miao-Hui, Yang, Hsiu-Chen, Wang, Yu-Chieh, Chen, Ying-Pin, Lin, Kai-Jen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309557/ https://www.ncbi.nlm.nih.gov/pubmed/25629609 http://dx.doi.org/10.1371/journal.pone.0117268 |
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