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10-Year Risk Estimation for Type 2 Diabetes Mellitus and Coronary Heart Disease in Kuwait: A Cross-Sectional Population-Based Study

BACKGROUND: Type 2 diabetes mellitus (T2DM), coronary heart disease (CHD) and metabolic syndrome (MetS) are major healthcare problems in Kuwait. The present study was designed to determine the prevalence of MetS, and to estimate the 10-year risk for developing T2DM and CHD among the general populati...

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Autores principales: Awad, Abdelmoneim Ismail, Alsaleh, Fatemah Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309592/
https://www.ncbi.nlm.nih.gov/pubmed/25629920
http://dx.doi.org/10.1371/journal.pone.0116742
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author Awad, Abdelmoneim Ismail
Alsaleh, Fatemah Mohammad
author_facet Awad, Abdelmoneim Ismail
Alsaleh, Fatemah Mohammad
author_sort Awad, Abdelmoneim Ismail
collection PubMed
description BACKGROUND: Type 2 diabetes mellitus (T2DM), coronary heart disease (CHD) and metabolic syndrome (MetS) are major healthcare problems in Kuwait. The present study was designed to determine the prevalence of MetS, and to estimate the 10-year risk for developing T2DM and CHD among the general population in Kuwait. METHODS: A descriptive, cross-sectional survey was undertaken in 1800 individuals without diabetes or a history of cardiovascular disease (CVD). They were selected from six governorates using two stage convenience sampling. The questionnaire was developed using the Finnish Diabetes Risk Score (FINDRISK), Framingham Risk Score [FRS] and the 2009 Joint Statement criteria for diagnosis of MetS as a framework. Descriptive and multivariate logistic regression analyses were used. RESULTS: The response rate was 89.4%. More than half (60.8%; 95% CI: 58.4–63.2) of responders were either overweight or obese. One hundred and ninety seven (12.2%) subjects had blood pressure (BP) ≥ 140/90 mm Hg. Almost three-in-ten (28.3%: 26.2–30.6) subjects had fasting plasma glucose (FPG) levels ≥ 5.6 mmol/l, of whom 86.0% and 14.0% had impaired fasting glucose (IFG) and screen detected T2DM, respectively. MetS was present in 512 (31.8%; 29.5–34.2) respondents. Just under one third (n = 481; 29.9%; 27.7–32.2) of participants were at moderate, high, or very high risk of developing T2DM, while 283 (17.6%: 15.8–19.6) were at moderate/high 10-year risk of developing CHD. Approximately one-in-ten (8.5%; 7.2–9.9) subjects were at moderate/high/very high 10-year risk of developing both T2DM/CHD. T2DM risk was higher for females compared to males (p < 0.001); however, the pattern was reversed in terms of the risk of developing CHD or T2DM/CHD. The risk of developing T2DM, CHD, or T2DM/CHD was greater among those aged ≥ 45 years, and those having MetS (p<0.001). CONCLUSIONS: The current findings highlight the need for multifaceted interventions for prevention.
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spelling pubmed-43095922015-02-06 10-Year Risk Estimation for Type 2 Diabetes Mellitus and Coronary Heart Disease in Kuwait: A Cross-Sectional Population-Based Study Awad, Abdelmoneim Ismail Alsaleh, Fatemah Mohammad PLoS One Research Article BACKGROUND: Type 2 diabetes mellitus (T2DM), coronary heart disease (CHD) and metabolic syndrome (MetS) are major healthcare problems in Kuwait. The present study was designed to determine the prevalence of MetS, and to estimate the 10-year risk for developing T2DM and CHD among the general population in Kuwait. METHODS: A descriptive, cross-sectional survey was undertaken in 1800 individuals without diabetes or a history of cardiovascular disease (CVD). They were selected from six governorates using two stage convenience sampling. The questionnaire was developed using the Finnish Diabetes Risk Score (FINDRISK), Framingham Risk Score [FRS] and the 2009 Joint Statement criteria for diagnosis of MetS as a framework. Descriptive and multivariate logistic regression analyses were used. RESULTS: The response rate was 89.4%. More than half (60.8%; 95% CI: 58.4–63.2) of responders were either overweight or obese. One hundred and ninety seven (12.2%) subjects had blood pressure (BP) ≥ 140/90 mm Hg. Almost three-in-ten (28.3%: 26.2–30.6) subjects had fasting plasma glucose (FPG) levels ≥ 5.6 mmol/l, of whom 86.0% and 14.0% had impaired fasting glucose (IFG) and screen detected T2DM, respectively. MetS was present in 512 (31.8%; 29.5–34.2) respondents. Just under one third (n = 481; 29.9%; 27.7–32.2) of participants were at moderate, high, or very high risk of developing T2DM, while 283 (17.6%: 15.8–19.6) were at moderate/high 10-year risk of developing CHD. Approximately one-in-ten (8.5%; 7.2–9.9) subjects were at moderate/high/very high 10-year risk of developing both T2DM/CHD. T2DM risk was higher for females compared to males (p < 0.001); however, the pattern was reversed in terms of the risk of developing CHD or T2DM/CHD. The risk of developing T2DM, CHD, or T2DM/CHD was greater among those aged ≥ 45 years, and those having MetS (p<0.001). CONCLUSIONS: The current findings highlight the need for multifaceted interventions for prevention. Public Library of Science 2015-01-28 /pmc/articles/PMC4309592/ /pubmed/25629920 http://dx.doi.org/10.1371/journal.pone.0116742 Text en © 2015 Awad, Alsaleh http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Awad, Abdelmoneim Ismail
Alsaleh, Fatemah Mohammad
10-Year Risk Estimation for Type 2 Diabetes Mellitus and Coronary Heart Disease in Kuwait: A Cross-Sectional Population-Based Study
title 10-Year Risk Estimation for Type 2 Diabetes Mellitus and Coronary Heart Disease in Kuwait: A Cross-Sectional Population-Based Study
title_full 10-Year Risk Estimation for Type 2 Diabetes Mellitus and Coronary Heart Disease in Kuwait: A Cross-Sectional Population-Based Study
title_fullStr 10-Year Risk Estimation for Type 2 Diabetes Mellitus and Coronary Heart Disease in Kuwait: A Cross-Sectional Population-Based Study
title_full_unstemmed 10-Year Risk Estimation for Type 2 Diabetes Mellitus and Coronary Heart Disease in Kuwait: A Cross-Sectional Population-Based Study
title_short 10-Year Risk Estimation for Type 2 Diabetes Mellitus and Coronary Heart Disease in Kuwait: A Cross-Sectional Population-Based Study
title_sort 10-year risk estimation for type 2 diabetes mellitus and coronary heart disease in kuwait: a cross-sectional population-based study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309592/
https://www.ncbi.nlm.nih.gov/pubmed/25629920
http://dx.doi.org/10.1371/journal.pone.0116742
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