Proteasomes, Sir2, and Hxk2 Form an Interconnected Aging Network That Impinges on the AMPK/Snf1-Regulated Transcriptional Repressor Mig1

Elevated proteasome activity extends lifespan in model organisms such as yeast, worms and flies. This pro-longevity effect might be mediated by improved protein homeostasis, as this protease is an integral module of the protein homeostasis network. Proteasomes also regulate cellular processes throug...

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Detalles Bibliográficos
Autores principales: Yao, Yanhua, Tsuchiyama, Scott, Yang, Ciyu, Bulteau, Anne Laure, He, Chong, Robison, Brett, Tsuchiya, Mitsuhiro, Miller, Delana, Briones, Valeria, Tar, Krisztina, Potrero, Anahi, Friguet, Bertrand, Kennedy, Brian K., Schmidt, Marion
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309596/
https://www.ncbi.nlm.nih.gov/pubmed/25629410
http://dx.doi.org/10.1371/journal.pgen.1004968

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