Antagonistic Cross-Regulation between Sox9 and Sox10 Controls an Anti-tumorigenic Program in Melanoma

Melanoma is the most fatal skin cancer, but the etiology of this devastating disease is still poorly understood. Recently, the transcription factor Sox10 has been shown to promote both melanoma initiation and progression. Reducing SOX10 expression levels in human melanoma cells and in a genetic mela...

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Detalles Bibliográficos
Autores principales: Shakhova, Olga, Cheng, Phil, Mishra, Pravin J., Zingg, Daniel, Schaefer, Simon M., Debbache, Julien, Häusel, Jessica, Matter, Claudia, Guo, Theresa, Davis, Sean, Meltzer, Paul, Mihic-Probst, Daniela, Moch, Holger, Wegner, Michael, Merlino, Glenn, Levesque, Mitchell P., Dummer, Reinhard, Santoro, Raffaella, Cinelli, Paolo, Sommer, Lukas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309598/
https://www.ncbi.nlm.nih.gov/pubmed/25629959
http://dx.doi.org/10.1371/journal.pgen.1004877

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