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Multifunction hexagonal liquid-crystal containing modified surface TiO(2) nanoparticles and terpinen-4-ol for controlled release
Multifunctional products have been developed to combine the benefits of functional components and terpinen-4-ol (TP) delivery systems. In this way, p-toluene sulfonic acid modified titanium dioxide (TiO(2)) nanoparticles and TP, an antioxidant, have been incorporated in liquid-crystalline formulatio...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309795/ https://www.ncbi.nlm.nih.gov/pubmed/25653523 http://dx.doi.org/10.2147/IJN.S71980 |
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author | Manaia, Eloísa Berbel Kaminski, Renata Cristina Kiatkoski de Oliveira, Anselmo Gomes Corrêa, Marcos Antonio Chiavacci, Leila Aparecida |
author_facet | Manaia, Eloísa Berbel Kaminski, Renata Cristina Kiatkoski de Oliveira, Anselmo Gomes Corrêa, Marcos Antonio Chiavacci, Leila Aparecida |
author_sort | Manaia, Eloísa Berbel |
collection | PubMed |
description | Multifunctional products have been developed to combine the benefits of functional components and terpinen-4-ol (TP) delivery systems. In this way, p-toluene sulfonic acid modified titanium dioxide (TiO(2)) nanoparticles and TP, an antioxidant, have been incorporated in liquid-crystalline formulations for photoprotection and controlled release of the TP, respectively. By X-ray powder diffraction and diffuse reflectance spectroscopy, we noted that using p-toluene sulfonic acid as a surface modifier made it possible to obtain smaller and more transparent TiO(2) nanoparticles than those commercially available. The liquid-crystalline formulation containing the inorganic ultraviolet filter was classified as broad-spectrum performance by the absorbance spectroscopy measurements. The formulations containing modified TiO(2) nanoparticles and TP were determined to be in the hexagonal phase by polarized light microscopy and small-angle X-ray scattering, which makes possible the controlled released of TP following zero-order kinetics. The developed formulations can control the release of TP. Constant concentrations of the substance have been released per time unit, and the modified TiO(2) nanoparticles can act as a transparent inorganic sunscreen. |
format | Online Article Text |
id | pubmed-4309795 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Dove Medical Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-43097952015-02-04 Multifunction hexagonal liquid-crystal containing modified surface TiO(2) nanoparticles and terpinen-4-ol for controlled release Manaia, Eloísa Berbel Kaminski, Renata Cristina Kiatkoski de Oliveira, Anselmo Gomes Corrêa, Marcos Antonio Chiavacci, Leila Aparecida Int J Nanomedicine Original Research Multifunctional products have been developed to combine the benefits of functional components and terpinen-4-ol (TP) delivery systems. In this way, p-toluene sulfonic acid modified titanium dioxide (TiO(2)) nanoparticles and TP, an antioxidant, have been incorporated in liquid-crystalline formulations for photoprotection and controlled release of the TP, respectively. By X-ray powder diffraction and diffuse reflectance spectroscopy, we noted that using p-toluene sulfonic acid as a surface modifier made it possible to obtain smaller and more transparent TiO(2) nanoparticles than those commercially available. The liquid-crystalline formulation containing the inorganic ultraviolet filter was classified as broad-spectrum performance by the absorbance spectroscopy measurements. The formulations containing modified TiO(2) nanoparticles and TP were determined to be in the hexagonal phase by polarized light microscopy and small-angle X-ray scattering, which makes possible the controlled released of TP following zero-order kinetics. The developed formulations can control the release of TP. Constant concentrations of the substance have been released per time unit, and the modified TiO(2) nanoparticles can act as a transparent inorganic sunscreen. Dove Medical Press 2015-01-22 /pmc/articles/PMC4309795/ /pubmed/25653523 http://dx.doi.org/10.2147/IJN.S71980 Text en © 2015 Manaia et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. |
spellingShingle | Original Research Manaia, Eloísa Berbel Kaminski, Renata Cristina Kiatkoski de Oliveira, Anselmo Gomes Corrêa, Marcos Antonio Chiavacci, Leila Aparecida Multifunction hexagonal liquid-crystal containing modified surface TiO(2) nanoparticles and terpinen-4-ol for controlled release |
title | Multifunction hexagonal liquid-crystal containing modified surface TiO(2) nanoparticles and terpinen-4-ol for controlled release |
title_full | Multifunction hexagonal liquid-crystal containing modified surface TiO(2) nanoparticles and terpinen-4-ol for controlled release |
title_fullStr | Multifunction hexagonal liquid-crystal containing modified surface TiO(2) nanoparticles and terpinen-4-ol for controlled release |
title_full_unstemmed | Multifunction hexagonal liquid-crystal containing modified surface TiO(2) nanoparticles and terpinen-4-ol for controlled release |
title_short | Multifunction hexagonal liquid-crystal containing modified surface TiO(2) nanoparticles and terpinen-4-ol for controlled release |
title_sort | multifunction hexagonal liquid-crystal containing modified surface tio(2) nanoparticles and terpinen-4-ol for controlled release |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309795/ https://www.ncbi.nlm.nih.gov/pubmed/25653523 http://dx.doi.org/10.2147/IJN.S71980 |
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