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Angiotensin Converting Enzyme Inhibitors (ACEI) and doxorubicin pharmacokinetics in women receiving adjuvant breast cancer treatment

PURPOSE: Doxorubicin (DOX) chemotherapy can cause cardiac complications. Angiotensin converting enzyme inhibitors (ACEI) may protect against these complications. We performed a pharmacokinetics (PK) study to determine whether DOX levels are altered in the presence of ACEI. METHODS: In this randomize...

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Detalles Bibliográficos
Autores principales: Blaes, Anne, Duprez, Daniel, Defor, Todd, Shanley, Ryan, Beckwith, Heather, Haddad, Tufia, Potter, David, Yee, Douglas, Sanghavi, Kinjal, Jacobson, Pamala
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309801/
https://www.ncbi.nlm.nih.gov/pubmed/25646154
http://dx.doi.org/10.1186/s40064-015-0802-4