Cargando…
Molecular mechanisms of the microsomal mixed function oxidases and biological and pathological implications
The cytochrome P450 mixed function oxidase enzymes play a major role in the metabolism of important endogenous substrates as well as in the biotransformation of xenobiotics. The liver P450 system is the most active in metabolism of exogenous substrates. This review briefly describes the liver P450 (...
Autor principal: | Cederbaum, Arthur I. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309856/ https://www.ncbi.nlm.nih.gov/pubmed/25498968 http://dx.doi.org/10.1016/j.redox.2014.11.008 |
Ejemplares similares
-
Methodology to assay CYP2E1 mixed function oxidase catalytic activity and its induction
por: Cederbaum, Arthur I.
Publicado: (2014) -
Inhibition of autophagy promotes CYP2E1-dependent toxicity in HepG2 cells via elevated oxidative stress, mitochondria dysfunction and activation of p38 and JNK MAPK()
por: Wu, Defeng, et al.
Publicado: (2013) -
MECHANISM OF THE CATION EFFECT IN SUBFRACTIONATION OF MICROSOMES
por: Dallner, Gustav, et al.
Publicado: (1966) -
NADPH Oxidases (NOX): An Overview from Discovery, Molecular Mechanisms to Physiology and Pathology
por: Vermot, Annelise, et al.
Publicado: (2021) -
ON THE MECHANISM OF DRUG HYDROXYLATION IN RAT LIVER MICROSOMES
por: Orrenius, Sten
Publicado: (1965)