Cargando…
Anti-inflammatory effects of BHBA in both in vivo and in vitro Parkinson’s disease models are mediated by GPR109A-dependent mechanisms
BACKGROUND: Accumulating evidence suggests that neuroinflammation plays an important role in the progression of Parkinson’s disease (PD). Excessively activated microglia produce several pro-inflammatory enzymes and pro-inflammatory cytokines, leading to damage to surrounding neurons and eventually i...
Autores principales: | Fu, Shou-Peng, Wang, Jian-Fa, Xue, Wen-Jing, Liu, Hong-Mei, Liu, Bing-run, Zeng, Ya-Long, Li, Su-Nan, Huang, Bing-Xu, Lv, Qing-Kang, Wang, Wei, Liu, Ju-Xiong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310035/ https://www.ncbi.nlm.nih.gov/pubmed/25595674 http://dx.doi.org/10.1186/s12974-014-0230-3 |
Ejemplares similares
-
BHBA Suppresses LPS-Induced Inflammation in BV-2 Cells by Inhibiting NF-κB Activation
por: Fu, Shou-Peng, et al.
Publicado: (2014) -
Upregulation of GPR109A in Parkinson’s Disease
por: Wakade, Chandramohan, et al.
Publicado: (2014) -
GPR109A and Vascular Inflammation
por: Chai, Joshua T., et al.
Publicado: (2013) -
Niacin Ameliorates Neuro-Inflammation in Parkinson’s Disease via GPR109A
por: Giri, Banabihari, et al.
Publicado: (2019) -
GPR109A activation and aging liver
por: Jadeja, Ravirajsinh N., et al.
Publicado: (2019)