In utero exposure to cigarette chemicals induces sex-specific disruption of one-carbon metabolism and DNA methylation in the human fetal liver

BACKGROUND: Maternal smoking is one of the most important modifiable risk factors for low birthweight, which is strongly associated with increased cardiometabolic disease risk in adulthood. Maternal smoking reduces the levels of the methyl donor vitamin B12 and is associated with altered DNA methyla...

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Detalles Bibliográficos
Autores principales: Drake, Amanda J, O’Shaughnessy, Peter J, Bhattacharya, Siladitya, Monteiro, Ana, Kerrigan, David, Goetz, Sven, Raab, Andrea, Rhind, Stewart M, Sinclair, Kevin D, Meharg, Andrew A, Feldmann, Jörg, Fowler, Paul A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310040/
https://www.ncbi.nlm.nih.gov/pubmed/25630355
http://dx.doi.org/10.1186/s12916-014-0251-x

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