Prostate laser vaporization is safe and effective in elderly men

INTRODUCTION: There are few data on the safety and efficacy of laser photoselective vaporization (LVP) in elderly men. We compared the safety and efficacy of LVP for the treatment of symptomatic benign prostatic hyperplasia (BPH) in men ≥75 years, who we defined as elderly, to those <75 years. MA...

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Autores principales: Majumdar, Rohit, Mirheydar, Hossein S., Palazzi, Kerrin L., Lakin, Charles M., Albo, Michael E., Parsons, J. Kellogg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310114/
https://www.ncbi.nlm.nih.gov/pubmed/25657541
http://dx.doi.org/10.4103/0974-7796.148595
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author Majumdar, Rohit
Mirheydar, Hossein S.
Palazzi, Kerrin L.
Lakin, Charles M.
Albo, Michael E.
Parsons, J. Kellogg
author_facet Majumdar, Rohit
Mirheydar, Hossein S.
Palazzi, Kerrin L.
Lakin, Charles M.
Albo, Michael E.
Parsons, J. Kellogg
author_sort Majumdar, Rohit
collection PubMed
description INTRODUCTION: There are few data on the safety and efficacy of laser photoselective vaporization (LVP) in elderly men. We compared the safety and efficacy of LVP for the treatment of symptomatic benign prostatic hyperplasia (BPH) in men ≥75 years, who we defined as elderly, to those <75 years. MATERIALS AND METHODS: Safety and efficacy outcomes in elderly men undergoing LVP for lower urinary tract symptoms secondary to BPH from 2005 to 2012 were compared with men <75 years. Differences between-groups in demographics, perioperative outcomes, complications, and postoperative changes in International Prostate Symptom Score (I-PSS) were calculated. RESULTS: Of 202 patients, 49 (24%) were elderly (range: 75-95 years) and 153 (76%) were <75 years. Preoperatively, elderly men were more likely to have heart disease (35% vs. 20%, P = 0.03), gross hematuria (6.1% vs. 0.7%, P = 0.05), urinary retention (57% vs. 41%, P = 0.07), and take anti-coagulants (61% vs. 35%, P = 0.002). Elderly men had a longer median length of stay (1 day vs. 0 day, P = 0.001). There were no significant between-group differences in transfusion frequency (4.4% vs. 0.7%, P = 0.14) or Clavien III complications (2% vs. 2.6%, P = 1.0). One month postsurgery, elderly patients reported smaller median decreases in I-PSS (5.5 vs. 9, P = 0.02) and urinary bother (1 point vs. 2, P = 0.03) compared with preoperative values. At till 9 months follow-up, there were no significant between-group differences in median I-PSS or urinary bother scores. CONCLUSIONS: Despite a higher prevalence of preoperative comorbidity and urinary retention, elderly LVP patients experienced perioperative safety and shorter term efficacy outcomes comparable to younger men.
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spelling pubmed-43101142015-02-05 Prostate laser vaporization is safe and effective in elderly men Majumdar, Rohit Mirheydar, Hossein S. Palazzi, Kerrin L. Lakin, Charles M. Albo, Michael E. Parsons, J. Kellogg Urol Ann Original Article INTRODUCTION: There are few data on the safety and efficacy of laser photoselective vaporization (LVP) in elderly men. We compared the safety and efficacy of LVP for the treatment of symptomatic benign prostatic hyperplasia (BPH) in men ≥75 years, who we defined as elderly, to those <75 years. MATERIALS AND METHODS: Safety and efficacy outcomes in elderly men undergoing LVP for lower urinary tract symptoms secondary to BPH from 2005 to 2012 were compared with men <75 years. Differences between-groups in demographics, perioperative outcomes, complications, and postoperative changes in International Prostate Symptom Score (I-PSS) were calculated. RESULTS: Of 202 patients, 49 (24%) were elderly (range: 75-95 years) and 153 (76%) were <75 years. Preoperatively, elderly men were more likely to have heart disease (35% vs. 20%, P = 0.03), gross hematuria (6.1% vs. 0.7%, P = 0.05), urinary retention (57% vs. 41%, P = 0.07), and take anti-coagulants (61% vs. 35%, P = 0.002). Elderly men had a longer median length of stay (1 day vs. 0 day, P = 0.001). There were no significant between-group differences in transfusion frequency (4.4% vs. 0.7%, P = 0.14) or Clavien III complications (2% vs. 2.6%, P = 1.0). One month postsurgery, elderly patients reported smaller median decreases in I-PSS (5.5 vs. 9, P = 0.02) and urinary bother (1 point vs. 2, P = 0.03) compared with preoperative values. At till 9 months follow-up, there were no significant between-group differences in median I-PSS or urinary bother scores. CONCLUSIONS: Despite a higher prevalence of preoperative comorbidity and urinary retention, elderly LVP patients experienced perioperative safety and shorter term efficacy outcomes comparable to younger men. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4310114/ /pubmed/25657541 http://dx.doi.org/10.4103/0974-7796.148595 Text en Copyright: © Urology Annals http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Majumdar, Rohit
Mirheydar, Hossein S.
Palazzi, Kerrin L.
Lakin, Charles M.
Albo, Michael E.
Parsons, J. Kellogg
Prostate laser vaporization is safe and effective in elderly men
title Prostate laser vaporization is safe and effective in elderly men
title_full Prostate laser vaporization is safe and effective in elderly men
title_fullStr Prostate laser vaporization is safe and effective in elderly men
title_full_unstemmed Prostate laser vaporization is safe and effective in elderly men
title_short Prostate laser vaporization is safe and effective in elderly men
title_sort prostate laser vaporization is safe and effective in elderly men
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310114/
https://www.ncbi.nlm.nih.gov/pubmed/25657541
http://dx.doi.org/10.4103/0974-7796.148595
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