Prostate laser vaporization is safe and effective in elderly men
INTRODUCTION: There are few data on the safety and efficacy of laser photoselective vaporization (LVP) in elderly men. We compared the safety and efficacy of LVP for the treatment of symptomatic benign prostatic hyperplasia (BPH) in men ≥75 years, who we defined as elderly, to those <75 years. MA...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Medknow Publications & Media Pvt Ltd
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310114/ https://www.ncbi.nlm.nih.gov/pubmed/25657541 http://dx.doi.org/10.4103/0974-7796.148595 |
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author | Majumdar, Rohit Mirheydar, Hossein S. Palazzi, Kerrin L. Lakin, Charles M. Albo, Michael E. Parsons, J. Kellogg |
author_facet | Majumdar, Rohit Mirheydar, Hossein S. Palazzi, Kerrin L. Lakin, Charles M. Albo, Michael E. Parsons, J. Kellogg |
author_sort | Majumdar, Rohit |
collection | PubMed |
description | INTRODUCTION: There are few data on the safety and efficacy of laser photoselective vaporization (LVP) in elderly men. We compared the safety and efficacy of LVP for the treatment of symptomatic benign prostatic hyperplasia (BPH) in men ≥75 years, who we defined as elderly, to those <75 years. MATERIALS AND METHODS: Safety and efficacy outcomes in elderly men undergoing LVP for lower urinary tract symptoms secondary to BPH from 2005 to 2012 were compared with men <75 years. Differences between-groups in demographics, perioperative outcomes, complications, and postoperative changes in International Prostate Symptom Score (I-PSS) were calculated. RESULTS: Of 202 patients, 49 (24%) were elderly (range: 75-95 years) and 153 (76%) were <75 years. Preoperatively, elderly men were more likely to have heart disease (35% vs. 20%, P = 0.03), gross hematuria (6.1% vs. 0.7%, P = 0.05), urinary retention (57% vs. 41%, P = 0.07), and take anti-coagulants (61% vs. 35%, P = 0.002). Elderly men had a longer median length of stay (1 day vs. 0 day, P = 0.001). There were no significant between-group differences in transfusion frequency (4.4% vs. 0.7%, P = 0.14) or Clavien III complications (2% vs. 2.6%, P = 1.0). One month postsurgery, elderly patients reported smaller median decreases in I-PSS (5.5 vs. 9, P = 0.02) and urinary bother (1 point vs. 2, P = 0.03) compared with preoperative values. At till 9 months follow-up, there were no significant between-group differences in median I-PSS or urinary bother scores. CONCLUSIONS: Despite a higher prevalence of preoperative comorbidity and urinary retention, elderly LVP patients experienced perioperative safety and shorter term efficacy outcomes comparable to younger men. |
format | Online Article Text |
id | pubmed-4310114 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-43101142015-02-05 Prostate laser vaporization is safe and effective in elderly men Majumdar, Rohit Mirheydar, Hossein S. Palazzi, Kerrin L. Lakin, Charles M. Albo, Michael E. Parsons, J. Kellogg Urol Ann Original Article INTRODUCTION: There are few data on the safety and efficacy of laser photoselective vaporization (LVP) in elderly men. We compared the safety and efficacy of LVP for the treatment of symptomatic benign prostatic hyperplasia (BPH) in men ≥75 years, who we defined as elderly, to those <75 years. MATERIALS AND METHODS: Safety and efficacy outcomes in elderly men undergoing LVP for lower urinary tract symptoms secondary to BPH from 2005 to 2012 were compared with men <75 years. Differences between-groups in demographics, perioperative outcomes, complications, and postoperative changes in International Prostate Symptom Score (I-PSS) were calculated. RESULTS: Of 202 patients, 49 (24%) were elderly (range: 75-95 years) and 153 (76%) were <75 years. Preoperatively, elderly men were more likely to have heart disease (35% vs. 20%, P = 0.03), gross hematuria (6.1% vs. 0.7%, P = 0.05), urinary retention (57% vs. 41%, P = 0.07), and take anti-coagulants (61% vs. 35%, P = 0.002). Elderly men had a longer median length of stay (1 day vs. 0 day, P = 0.001). There were no significant between-group differences in transfusion frequency (4.4% vs. 0.7%, P = 0.14) or Clavien III complications (2% vs. 2.6%, P = 1.0). One month postsurgery, elderly patients reported smaller median decreases in I-PSS (5.5 vs. 9, P = 0.02) and urinary bother (1 point vs. 2, P = 0.03) compared with preoperative values. At till 9 months follow-up, there were no significant between-group differences in median I-PSS or urinary bother scores. CONCLUSIONS: Despite a higher prevalence of preoperative comorbidity and urinary retention, elderly LVP patients experienced perioperative safety and shorter term efficacy outcomes comparable to younger men. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4310114/ /pubmed/25657541 http://dx.doi.org/10.4103/0974-7796.148595 Text en Copyright: © Urology Annals http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Majumdar, Rohit Mirheydar, Hossein S. Palazzi, Kerrin L. Lakin, Charles M. Albo, Michael E. Parsons, J. Kellogg Prostate laser vaporization is safe and effective in elderly men |
title | Prostate laser vaporization is safe and effective in elderly men |
title_full | Prostate laser vaporization is safe and effective in elderly men |
title_fullStr | Prostate laser vaporization is safe and effective in elderly men |
title_full_unstemmed | Prostate laser vaporization is safe and effective in elderly men |
title_short | Prostate laser vaporization is safe and effective in elderly men |
title_sort | prostate laser vaporization is safe and effective in elderly men |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310114/ https://www.ncbi.nlm.nih.gov/pubmed/25657541 http://dx.doi.org/10.4103/0974-7796.148595 |
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