Structural importance of the C-terminal region in pig aldo-keto reductase family 1 member C1 and their effects on enzymatic activity

BACKGROUND: Pig aldo-keto reductase family 1 member C1 (AKR1C1) belongs to AKR superfamily which catalyzes the NAD(P)H-dependent reduction of various substrates including steroid hormones. Previously we have reported two paralogous pig AKR1C1s, wild-type AKR1C1 (C-type) and C-terminal-truncated AKR1...

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Detalles Bibliográficos
Autores principales: Son, Minky, Park, Chanin, Kwon, Seul Gi, Bang, Woo Young, Kim, Sam Woong, Kim, Chul Wook, Lee, Keun Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310174/
https://www.ncbi.nlm.nih.gov/pubmed/25583233
http://dx.doi.org/10.1186/s12900-014-0028-7

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