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Intradialytic Hypotension and Cardiac Remodeling: A Vicious Cycle
Hemodynamic instability during hemodialysis is a common but often underestimated issue in the nephrologist practice. Intradialytic hypotension, namely, a decrease of systolic or mean blood pressure to a certain level, prohibits the safe and smooth achievement of ultrafiltration and solute removal go...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310253/ https://www.ncbi.nlm.nih.gov/pubmed/25654122 http://dx.doi.org/10.1155/2015/724147 |
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author | Chao, Chia-Ter Huang, Jenq-Wen Yen, Chung-Jen |
author_facet | Chao, Chia-Ter Huang, Jenq-Wen Yen, Chung-Jen |
author_sort | Chao, Chia-Ter |
collection | PubMed |
description | Hemodynamic instability during hemodialysis is a common but often underestimated issue in the nephrologist practice. Intradialytic hypotension, namely, a decrease of systolic or mean blood pressure to a certain level, prohibits the safe and smooth achievement of ultrafiltration and solute removal goal in chronic dialysis patients. Studies have elucidated the potential mechanisms involved in the development of Intradialytic hypotension, including excessive ultrafiltration and loss of compensatory mechanisms for blood pressure maintenance. Cardiac remodeling could also be one important piece of the puzzle. In this review, we intend to discuss the role of cardiac remodeling, including left ventricular hypertrophy, in the development of Intradialytic hypotension. In addition, we will also provide evidence that a bidirectional relationship might exist between Intradialytic hypotension and left ventricular hypertrophy in chronic dialysis patients. A more complete understanding of the complex interactions in between could assist the readers in formulating potential solutions for the reduction of both phenomena. |
format | Online Article Text |
id | pubmed-4310253 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-43102532015-02-04 Intradialytic Hypotension and Cardiac Remodeling: A Vicious Cycle Chao, Chia-Ter Huang, Jenq-Wen Yen, Chung-Jen Biomed Res Int Review Article Hemodynamic instability during hemodialysis is a common but often underestimated issue in the nephrologist practice. Intradialytic hypotension, namely, a decrease of systolic or mean blood pressure to a certain level, prohibits the safe and smooth achievement of ultrafiltration and solute removal goal in chronic dialysis patients. Studies have elucidated the potential mechanisms involved in the development of Intradialytic hypotension, including excessive ultrafiltration and loss of compensatory mechanisms for blood pressure maintenance. Cardiac remodeling could also be one important piece of the puzzle. In this review, we intend to discuss the role of cardiac remodeling, including left ventricular hypertrophy, in the development of Intradialytic hypotension. In addition, we will also provide evidence that a bidirectional relationship might exist between Intradialytic hypotension and left ventricular hypertrophy in chronic dialysis patients. A more complete understanding of the complex interactions in between could assist the readers in formulating potential solutions for the reduction of both phenomena. Hindawi Publishing Corporation 2015 2015-01-14 /pmc/articles/PMC4310253/ /pubmed/25654122 http://dx.doi.org/10.1155/2015/724147 Text en Copyright © 2015 Chia-Ter Chao et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Chao, Chia-Ter Huang, Jenq-Wen Yen, Chung-Jen Intradialytic Hypotension and Cardiac Remodeling: A Vicious Cycle |
title | Intradialytic Hypotension and Cardiac Remodeling: A Vicious Cycle |
title_full | Intradialytic Hypotension and Cardiac Remodeling: A Vicious Cycle |
title_fullStr | Intradialytic Hypotension and Cardiac Remodeling: A Vicious Cycle |
title_full_unstemmed | Intradialytic Hypotension and Cardiac Remodeling: A Vicious Cycle |
title_short | Intradialytic Hypotension and Cardiac Remodeling: A Vicious Cycle |
title_sort | intradialytic hypotension and cardiac remodeling: a vicious cycle |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310253/ https://www.ncbi.nlm.nih.gov/pubmed/25654122 http://dx.doi.org/10.1155/2015/724147 |
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