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Tetrahydrocannabinol Induces Brain Mitochondrial Respiratory Chain Dysfunction and Increases Oxidative Stress: A Potential Mechanism Involved in Cannabis-Related Stroke

Cannabis has potential therapeutic use but tetrahydrocannabinol (THC), its main psychoactive component, appears as a risk factor for ischemic stroke in young adults. We therefore evaluate the effects of THC on brain mitochondrial function and oxidative stress, key factors involved in stroke. Maximal...

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Detalles Bibliográficos
Autores principales: Wolff, Valérie, Schlagowski, Anna-Isabel, Rouyer, Olivier, Charles, Anne-Laure, Singh, François, Auger, Cyril, Schini-Kerth, Valérie, Marescaux, Christian, Raul, Jean-Sébastien, Zoll, Joffrey, Geny, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310259/
https://www.ncbi.nlm.nih.gov/pubmed/25654095
http://dx.doi.org/10.1155/2015/323706