Mechanisms of Translocation of ER Chaperones to the Cell Surface and Immunomodulatory Roles in Cancer and Autoimmunity

Endoplasmic reticulum (ER) chaperones (e.g., calreticulin, heat shock proteins, and isomerases) perform a multitude of functions within the ER. However, many of these chaperones can translocate to the cytosol and eventually the surface of cells, particularly during ER stress induced by e.g., drugs,...

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Detalles Bibliográficos
Autores principales: Wiersma, Valerie R., Michalak, Marek, Abdullah, Trefa M., Bremer, Edwin, Eggleton, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310273/
https://www.ncbi.nlm.nih.gov/pubmed/25688334
http://dx.doi.org/10.3389/fonc.2015.00007