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Current Therapeutic Advances Targeting EGFR and EGFRvIII in Glioblastoma

Epidermal growth factor receptor (EGFR) and EGFRvIII analysis is of current interest in glioblastoma – the most common malignant primary CNS tumor, because of new EGFRvIII vaccine trials underway. EGFR activation in glioblastoma promotes cellular proliferation via activation of MAPK and PI3K–Akt pat...

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Detalles Bibliográficos
Autores principales:	Padfield, Emily, Ellis, Hayley P., Kurian, Kathreena M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310282/ https://www.ncbi.nlm.nih.gov/pubmed/25688333 http://dx.doi.org/10.3389/fonc.2015.00005

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