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Werner Syndrome-specific induced pluripotent stem cells: recovery of telomere function by reprogramming
Werner syndrome (WS) is a rare human autosomal recessive premature aging disorder characterized by early onset of aging-associated diseases, chromosomal instability, and cancer predisposition. The function of the DNA helicase encoded by WRN, the gene responsible for WS, has been studied extensively....
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310323/ https://www.ncbi.nlm.nih.gov/pubmed/25688260 http://dx.doi.org/10.3389/fgene.2015.00010 |