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Werner Syndrome-specific induced pluripotent stem cells: recovery of telomere function by reprogramming

Werner syndrome (WS) is a rare human autosomal recessive premature aging disorder characterized by early onset of aging-associated diseases, chromosomal instability, and cancer predisposition. The function of the DNA helicase encoded by WRN, the gene responsible for WS, has been studied extensively....

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Detalles Bibliográficos
Autores principales:	Shimamoto, Akira, Yokote, Koutaro, Tahara, Hidetoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310323/ https://www.ncbi.nlm.nih.gov/pubmed/25688260 http://dx.doi.org/10.3389/fgene.2015.00010

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