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Chronic Hypoxemia in Late Gestation Decreases Cardiomyocyte Number but Does Not Change Expression of Hypoxia‐Responsive Genes
BACKGROUND: Placental insufficiency is the leading cause of intrauterine growth restriction in the developed world and results in chronic hypoxemia in the fetus. Oxygen is essential for fetal heart development, but a hypoxemic environment in utero can permanently alter development of cardiomyocytes....
Autores principales: | Botting, Kimberley J., McMillen, I. Caroline, Forbes, Heather, Nyengaard, Jens R., Morrison, Janna L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310356/ https://www.ncbi.nlm.nih.gov/pubmed/25085511 http://dx.doi.org/10.1161/JAHA.113.000531 |
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