Early Activation of the Kynurenine Pathway Predicts Early Death and Long‐term Outcome in Patients Resuscitated From Out‐of‐Hospital Cardiac Arrest

BACKGROUND: The kynurenine pathway (KP) is the major route of tryptophan (TRP) catabolism and is activated by inflammation and after cardiac arrest in animals. We hypothesized that the KP activation level correlates with severity of post–cardiac arrest shock, early death, and long‐term outcome. METH...

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Detalles Bibliográficos
Autores principales: Ristagno, Giuseppe, Latini, Roberto, Vaahersalo, Jukka, Masson, Serge, Kurola, Jouni, Varpula, Tero, Lucchetti, Jacopo, Fracasso, Claudia, Guiso, Giovanna, Montanelli, Alessandro, Barlera, Simona, Gobbi, Marco, Tiainen, Marjaana, Pettilä, Ville, Skrifvars, Markus B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310405/
https://www.ncbi.nlm.nih.gov/pubmed/25092787
http://dx.doi.org/10.1161/JAHA.114.001094

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