Renal denervation of the native kidneys for drug-resistant hypertension after kidney transplantation

There is a strong rationale for renal denervation (RDN) of the native kidneys in kidney transplant recipients with treatment-resistant hypertension. We present a patient with a stable graft function, who underwent RDN for posttransplant therapy-resistant hypertension (24-h ambulatory blood pressure...

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Detalles Bibliográficos
Autores principales: Dobrowolski, Linn C., Bemelman, Frederike J., ten Berge, Ineke J.M., van den Born, Bert-Jan H., Reekers, Jim A., Krediet, C.T. Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Contents
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310436/
https://www.ncbi.nlm.nih.gov/pubmed/25713714
http://dx.doi.org/10.1093/ckj/sfu134
Descripción
Sumario:There is a strong rationale for renal denervation (RDN) of the native kidneys in kidney transplant recipients with treatment-resistant hypertension. We present a patient with a stable graft function, who underwent RDN for posttransplant therapy-resistant hypertension (24-h ambulatory blood pressure measurement (ABPM) 143/89 mmHg, while compliantly using five different antihypertensive agents). After RDN, BP measurements and orthostatic complaints required withdrawal of two antihypertensive agents and halving a third. At 6 months, ABPM was 134/84 mmHg and allograft function remained unchanged. This case calls for designing well-designed prospective studies on RDN in kidney transplant recipients.

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