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Pien Tze Huang Inhibits Hypoxia-Induced Angiogenesis via HIF-1α/VEGF-A Pathway in Colorectal Cancer

Hypoxia-induced angiogenesis plays an important role in the development and metastasis of solid tumors and is highly regulated by HIF-1α/VEGF-A pathway. Therefore, inhibiting tumor angiogenesis via suppression of HIF-1α/VEGF-A signaling represents a promising strategy for anticancer treatment. As a...

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Detalles Bibliográficos
Autores principales: Chen, Hongwei, Feng, Jianyu, Zhang, Yuchen, Shen, Aling, Chen, Youqin, Lin, Jiumao, Lin, Wei, Sferra, Thomas J., Peng, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310443/
https://www.ncbi.nlm.nih.gov/pubmed/25649293
http://dx.doi.org/10.1155/2015/454279