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Intradural Solitary Fibrous Tumor of the Lumbar Spine: A Distinctive Case Report

Background. Solitary fibrous tumors are ubiquitous mesenchymal neoplasms of putative fibroblastic origin. They were originally described in the pleura but subsequently have been reported in many extraserosal sites. Solitary fibrous tumors may also occur in the meninges, central nervous system parenc...

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Autores principales: Basaran, Recep, Kaksi, Mustafa, Onoz, Mustafa, Balkuv, Ece, Sav, Aydin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310453/
https://www.ncbi.nlm.nih.gov/pubmed/25648160
http://dx.doi.org/10.1155/2015/708472
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author Basaran, Recep
Kaksi, Mustafa
Onoz, Mustafa
Balkuv, Ece
Sav, Aydin
author_facet Basaran, Recep
Kaksi, Mustafa
Onoz, Mustafa
Balkuv, Ece
Sav, Aydin
author_sort Basaran, Recep
collection PubMed
description Background. Solitary fibrous tumors are ubiquitous mesenchymal neoplasms of putative fibroblastic origin. They were originally described in the pleura but subsequently have been reported in many extraserosal sites. Solitary fibrous tumors may also occur in the meninges, central nervous system parenchyma, and spinal cord. Case. A 67-year-old male patient with progressive lower extremity weakness, urinary urgency, and sexual dysfunction has been admitted to our hospital. On his lumbar MRI, we detected an intradural lesion posterior to the L3 vertebral corpus. We resected the lesion by L3 total laminectomy. Immunohistological findings revealed strong and diffuse immunopositivity with vimentin, CD34, and bcl-2. Ki-67 proliferation index was 5–8%. We did not detect any recurrence 12 months after his operation. Conclusion. SFT is mostly seen in young and middle-aged patients and should be considered among differential diagnosis in cases suffering from pain, hypoesthesia, and urinary dysfunction. Gross total resection should be primary treatment. Tumors that have high Ki-67 labeling should be followed up for potential recurrences.
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spelling pubmed-43104532015-02-03 Intradural Solitary Fibrous Tumor of the Lumbar Spine: A Distinctive Case Report Basaran, Recep Kaksi, Mustafa Onoz, Mustafa Balkuv, Ece Sav, Aydin Case Rep Neurol Med Case Report Background. Solitary fibrous tumors are ubiquitous mesenchymal neoplasms of putative fibroblastic origin. They were originally described in the pleura but subsequently have been reported in many extraserosal sites. Solitary fibrous tumors may also occur in the meninges, central nervous system parenchyma, and spinal cord. Case. A 67-year-old male patient with progressive lower extremity weakness, urinary urgency, and sexual dysfunction has been admitted to our hospital. On his lumbar MRI, we detected an intradural lesion posterior to the L3 vertebral corpus. We resected the lesion by L3 total laminectomy. Immunohistological findings revealed strong and diffuse immunopositivity with vimentin, CD34, and bcl-2. Ki-67 proliferation index was 5–8%. We did not detect any recurrence 12 months after his operation. Conclusion. SFT is mostly seen in young and middle-aged patients and should be considered among differential diagnosis in cases suffering from pain, hypoesthesia, and urinary dysfunction. Gross total resection should be primary treatment. Tumors that have high Ki-67 labeling should be followed up for potential recurrences. Hindawi Publishing Corporation 2015 2015-01-14 /pmc/articles/PMC4310453/ /pubmed/25648160 http://dx.doi.org/10.1155/2015/708472 Text en Copyright © 2015 Recep Basaran et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Basaran, Recep
Kaksi, Mustafa
Onoz, Mustafa
Balkuv, Ece
Sav, Aydin
Intradural Solitary Fibrous Tumor of the Lumbar Spine: A Distinctive Case Report
title Intradural Solitary Fibrous Tumor of the Lumbar Spine: A Distinctive Case Report
title_full Intradural Solitary Fibrous Tumor of the Lumbar Spine: A Distinctive Case Report
title_fullStr Intradural Solitary Fibrous Tumor of the Lumbar Spine: A Distinctive Case Report
title_full_unstemmed Intradural Solitary Fibrous Tumor of the Lumbar Spine: A Distinctive Case Report
title_short Intradural Solitary Fibrous Tumor of the Lumbar Spine: A Distinctive Case Report
title_sort intradural solitary fibrous tumor of the lumbar spine: a distinctive case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310453/
https://www.ncbi.nlm.nih.gov/pubmed/25648160
http://dx.doi.org/10.1155/2015/708472
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