Cargando…
Intradural Solitary Fibrous Tumor of the Lumbar Spine: A Distinctive Case Report
Background. Solitary fibrous tumors are ubiquitous mesenchymal neoplasms of putative fibroblastic origin. They were originally described in the pleura but subsequently have been reported in many extraserosal sites. Solitary fibrous tumors may also occur in the meninges, central nervous system parenc...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310453/ https://www.ncbi.nlm.nih.gov/pubmed/25648160 http://dx.doi.org/10.1155/2015/708472 |
_version_ | 1782354879881150464 |
---|---|
author | Basaran, Recep Kaksi, Mustafa Onoz, Mustafa Balkuv, Ece Sav, Aydin |
author_facet | Basaran, Recep Kaksi, Mustafa Onoz, Mustafa Balkuv, Ece Sav, Aydin |
author_sort | Basaran, Recep |
collection | PubMed |
description | Background. Solitary fibrous tumors are ubiquitous mesenchymal neoplasms of putative fibroblastic origin. They were originally described in the pleura but subsequently have been reported in many extraserosal sites. Solitary fibrous tumors may also occur in the meninges, central nervous system parenchyma, and spinal cord. Case. A 67-year-old male patient with progressive lower extremity weakness, urinary urgency, and sexual dysfunction has been admitted to our hospital. On his lumbar MRI, we detected an intradural lesion posterior to the L3 vertebral corpus. We resected the lesion by L3 total laminectomy. Immunohistological findings revealed strong and diffuse immunopositivity with vimentin, CD34, and bcl-2. Ki-67 proliferation index was 5–8%. We did not detect any recurrence 12 months after his operation. Conclusion. SFT is mostly seen in young and middle-aged patients and should be considered among differential diagnosis in cases suffering from pain, hypoesthesia, and urinary dysfunction. Gross total resection should be primary treatment. Tumors that have high Ki-67 labeling should be followed up for potential recurrences. |
format | Online Article Text |
id | pubmed-4310453 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-43104532015-02-03 Intradural Solitary Fibrous Tumor of the Lumbar Spine: A Distinctive Case Report Basaran, Recep Kaksi, Mustafa Onoz, Mustafa Balkuv, Ece Sav, Aydin Case Rep Neurol Med Case Report Background. Solitary fibrous tumors are ubiquitous mesenchymal neoplasms of putative fibroblastic origin. They were originally described in the pleura but subsequently have been reported in many extraserosal sites. Solitary fibrous tumors may also occur in the meninges, central nervous system parenchyma, and spinal cord. Case. A 67-year-old male patient with progressive lower extremity weakness, urinary urgency, and sexual dysfunction has been admitted to our hospital. On his lumbar MRI, we detected an intradural lesion posterior to the L3 vertebral corpus. We resected the lesion by L3 total laminectomy. Immunohistological findings revealed strong and diffuse immunopositivity with vimentin, CD34, and bcl-2. Ki-67 proliferation index was 5–8%. We did not detect any recurrence 12 months after his operation. Conclusion. SFT is mostly seen in young and middle-aged patients and should be considered among differential diagnosis in cases suffering from pain, hypoesthesia, and urinary dysfunction. Gross total resection should be primary treatment. Tumors that have high Ki-67 labeling should be followed up for potential recurrences. Hindawi Publishing Corporation 2015 2015-01-14 /pmc/articles/PMC4310453/ /pubmed/25648160 http://dx.doi.org/10.1155/2015/708472 Text en Copyright © 2015 Recep Basaran et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Basaran, Recep Kaksi, Mustafa Onoz, Mustafa Balkuv, Ece Sav, Aydin Intradural Solitary Fibrous Tumor of the Lumbar Spine: A Distinctive Case Report |
title | Intradural Solitary Fibrous Tumor of the Lumbar Spine: A Distinctive Case Report |
title_full | Intradural Solitary Fibrous Tumor of the Lumbar Spine: A Distinctive Case Report |
title_fullStr | Intradural Solitary Fibrous Tumor of the Lumbar Spine: A Distinctive Case Report |
title_full_unstemmed | Intradural Solitary Fibrous Tumor of the Lumbar Spine: A Distinctive Case Report |
title_short | Intradural Solitary Fibrous Tumor of the Lumbar Spine: A Distinctive Case Report |
title_sort | intradural solitary fibrous tumor of the lumbar spine: a distinctive case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310453/ https://www.ncbi.nlm.nih.gov/pubmed/25648160 http://dx.doi.org/10.1155/2015/708472 |
work_keys_str_mv | AT basaranrecep intraduralsolitaryfibroustumorofthelumbarspineadistinctivecasereport AT kaksimustafa intraduralsolitaryfibroustumorofthelumbarspineadistinctivecasereport AT onozmustafa intraduralsolitaryfibroustumorofthelumbarspineadistinctivecasereport AT balkuvece intraduralsolitaryfibroustumorofthelumbarspineadistinctivecasereport AT savaydin intraduralsolitaryfibroustumorofthelumbarspineadistinctivecasereport |