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Superficial Tunica Albuginea Rupture as Initial Starting Point of Peyronie's Disease: A Topic for Interdisciplinary Consideration

Peyronie's disease is a connective tissue disorder in the soft tissue of the penis. The underlying cause of Peyronie's disease is not well understood but is thought to be caused by trauma or injury to the penis during sexual intercourse. The purpose of the interdisciplinary cooperation bet...

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Detalles Bibliográficos
Autores principales: Herwig, Ralf, Bayerl, Manfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310490/
https://www.ncbi.nlm.nih.gov/pubmed/25648614
http://dx.doi.org/10.1155/2015/751372
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author Herwig, Ralf
Bayerl, Manfred
author_facet Herwig, Ralf
Bayerl, Manfred
author_sort Herwig, Ralf
collection PubMed
description Peyronie's disease is a connective tissue disorder in the soft tissue of the penis. The underlying cause of Peyronie's disease is not well understood but is thought to be caused by trauma or injury to the penis during sexual intercourse. The purpose of the interdisciplinary cooperation between urological surgery and physics is the development of a physical simulation tool in order to give prognosis of possible tunica albuginea fibre rupture at a certain degree of deviation of the penis. For our group the first challenge was to translate the human organ of the penis into a physical model. Starting and marginal parameters had to be defined, whereby some of them had to be based on assumption, as physical data of the human living tissue have rarely been measured up to now. The algorithm and its dependencies had to be developed. This paper is a first step of a three-dimensional mathematical-physical simulation with the assumption of a 100% filled rigid penis. The calculation gives proof of the hypothesis that the fibre-load-angle of the penis is less than 12 degrees. Thus physical simulation is able to provide the surgeon with a simple instrument to calculate and forecast the risk of the individual patient.
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spelling pubmed-43104902015-02-03 Superficial Tunica Albuginea Rupture as Initial Starting Point of Peyronie's Disease: A Topic for Interdisciplinary Consideration Herwig, Ralf Bayerl, Manfred Biomed Res Int Research Article Peyronie's disease is a connective tissue disorder in the soft tissue of the penis. The underlying cause of Peyronie's disease is not well understood but is thought to be caused by trauma or injury to the penis during sexual intercourse. The purpose of the interdisciplinary cooperation between urological surgery and physics is the development of a physical simulation tool in order to give prognosis of possible tunica albuginea fibre rupture at a certain degree of deviation of the penis. For our group the first challenge was to translate the human organ of the penis into a physical model. Starting and marginal parameters had to be defined, whereby some of them had to be based on assumption, as physical data of the human living tissue have rarely been measured up to now. The algorithm and its dependencies had to be developed. This paper is a first step of a three-dimensional mathematical-physical simulation with the assumption of a 100% filled rigid penis. The calculation gives proof of the hypothesis that the fibre-load-angle of the penis is less than 12 degrees. Thus physical simulation is able to provide the surgeon with a simple instrument to calculate and forecast the risk of the individual patient. Hindawi Publishing Corporation 2015 2015-01-15 /pmc/articles/PMC4310490/ /pubmed/25648614 http://dx.doi.org/10.1155/2015/751372 Text en Copyright © 2015 R. Herwig and M. Bayerl. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Herwig, Ralf
Bayerl, Manfred
Superficial Tunica Albuginea Rupture as Initial Starting Point of Peyronie's Disease: A Topic for Interdisciplinary Consideration
title Superficial Tunica Albuginea Rupture as Initial Starting Point of Peyronie's Disease: A Topic for Interdisciplinary Consideration
title_full Superficial Tunica Albuginea Rupture as Initial Starting Point of Peyronie's Disease: A Topic for Interdisciplinary Consideration
title_fullStr Superficial Tunica Albuginea Rupture as Initial Starting Point of Peyronie's Disease: A Topic for Interdisciplinary Consideration
title_full_unstemmed Superficial Tunica Albuginea Rupture as Initial Starting Point of Peyronie's Disease: A Topic for Interdisciplinary Consideration
title_short Superficial Tunica Albuginea Rupture as Initial Starting Point of Peyronie's Disease: A Topic for Interdisciplinary Consideration
title_sort superficial tunica albuginea rupture as initial starting point of peyronie's disease: a topic for interdisciplinary consideration
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310490/
https://www.ncbi.nlm.nih.gov/pubmed/25648614
http://dx.doi.org/10.1155/2015/751372
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