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Diet Is Critical for Prolonged Glycemic Control after Short-Term Insulin Treatment in High-Fat Diet-Induced Type 2 Diabetic Male Mice
BACKGROUND: Clinical studies suggest that short-term insulin treatment in new-onset type 2 diabetes (T2DM) can promote prolonged glycemic control. The purpose of this study was to establish an animal model to examine such a “legacy” effect of early insulin therapy (EIT) in long-term glycemic control...
Autores principales: | Guo, Aili, Daniels, Nigel A., Thuma, Jean, McCall, Kelly D., Malgor, Ramiro, Schwartz, Frank L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310595/ https://www.ncbi.nlm.nih.gov/pubmed/25633992 http://dx.doi.org/10.1371/journal.pone.0117556 |
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