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Nephrokeli, a Chinese Herbal Formula, May Improve IgA Nephropathy through Regulation of the Sphingosine-1-Phosphate Pathway
Nephrokeli (NPKL) is a Chinese herbal formula that has been used to treat patients with IgA nephropathy (IgAN) for improvement of proteinuria and kidney injury. However, the mechanism remains unclear. Sphingosine-1-phosphate (S1P) and its receptors S1PR2 and S1PR3 are known to play an important role...
Autores principales: | Zhong, Yifei, Wang, Ke, Zhang, Xianwen, Cai, Xiaofan, Chen, Yiping, Deng, Yueyi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310606/ https://www.ncbi.nlm.nih.gov/pubmed/25633986 http://dx.doi.org/10.1371/journal.pone.0116873 |
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