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Enhancing Allosteric Inhibition in Thermus thermophilus Phosphofructokinase
[Image: see text] The coupling between the binding of the substrate Fru-6-P and the inhibitor phospho(enol)pyruvate (PEP) in phosphofructokinase (PFK) from the extreme thermophile Thermus thermophilus is much weaker than that seen in a PFK from Bacillus stearothermophilus. From the crystal structure...
Autores principales: | McGresham, Maria S., Reinhart, Gregory D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310622/ https://www.ncbi.nlm.nih.gov/pubmed/25531642 http://dx.doi.org/10.1021/bi501127a |
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