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Multiplex Detection of Functional G Protein-Coupled Receptors Harboring Site-Specifically Modified Unnatural Amino Acids

[Image: see text] We developed a strategy for identifying positions in G protein-coupled receptors that are amenable to bioorthogonal modification with a peptide epitope tag under cell culturing conditions. We introduced the unnatural amino acid p-azido-l-phenylalanine (azF) into human CC chemokine...

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Detalles Bibliográficos
Autores principales: Naganathan, Saranga, Ray-Saha, Sarmistha, Park, Minyoung, Tian, He, Sakmar, Thomas P., Huber, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310623/
https://www.ncbi.nlm.nih.gov/pubmed/25524496
http://dx.doi.org/10.1021/bi501267x