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Duration of Symptom and ABCD(2) Score as Predictors of Risk of Early Recurrent Events after Transient Ischemic Attack: A Hospital-Based Case Series Study

BACKGROUND: The aim of this study was to refine clinical risk factor stratification and make an optimal intervention plan to prevent ischemic stroke. MATERIAL/METHODS: Clinical data, including diffusion-weighted imaging (DWI) findings, were collected in a cohort of hospitalized transient ischemic at...

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Autores principales: Li, Qiang, Zhu, Xiaolong, Feng, Chao, Fang, Min, Liu, Xueyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310715/
https://www.ncbi.nlm.nih.gov/pubmed/25604068
http://dx.doi.org/10.12659/MSM.892525
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author Li, Qiang
Zhu, Xiaolong
Feng, Chao
Fang, Min
Liu, Xueyuan
author_facet Li, Qiang
Zhu, Xiaolong
Feng, Chao
Fang, Min
Liu, Xueyuan
author_sort Li, Qiang
collection PubMed
description BACKGROUND: The aim of this study was to refine clinical risk factor stratification and make an optimal intervention plan to prevent ischemic stroke. MATERIAL/METHODS: Clinical data, including diffusion-weighted imaging (DWI) findings, were collected in a cohort of hospitalized transient ischemic attack (TIA) patients from January 2010 to December 2011. Recurrent cerebrovascular events after TIA, including recurrent TIA, minor stroke, and major stroke, were identified by face-to-face follow-up. A multivariate, ordinal, logistic regression model was used to determine significant predictors of recurrent events. RESULTS: Of 106 TIA patients, 24 (22.6%) had recurrent TIA and 20 (18.9%) had a stroke within 7 days. Hypertension, dyslipidemia, a history of ischemic stroke or TIA, and ABCD(2) score were significantly associated with the recurrent events after TIA (P<0.001, P=0.02, P<0.001, P=0.02). Hypertension (RR=9.21; 95% CI, 3.07–27.61, P<0.001) and duration of symptom (RR=1.10; 95% CI, 1.02–1.17, P=0.01) as an item of ABCD(2) score were highly predictive of the severity of recurrent events, whereas ABCD(2) score as a whole (P=0.18) proved to be less strongly predictive. CONCLUSIONS: A history of hypertension and long duration of symptom independently and significantly predict severe recurrent events after TIA within 7 days, but a high ABCD(2) score was less strongly predictive of severe recurrent events.
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spelling pubmed-43107152015-01-30 Duration of Symptom and ABCD(2) Score as Predictors of Risk of Early Recurrent Events after Transient Ischemic Attack: A Hospital-Based Case Series Study Li, Qiang Zhu, Xiaolong Feng, Chao Fang, Min Liu, Xueyuan Med Sci Monit Clinical Research BACKGROUND: The aim of this study was to refine clinical risk factor stratification and make an optimal intervention plan to prevent ischemic stroke. MATERIAL/METHODS: Clinical data, including diffusion-weighted imaging (DWI) findings, were collected in a cohort of hospitalized transient ischemic attack (TIA) patients from January 2010 to December 2011. Recurrent cerebrovascular events after TIA, including recurrent TIA, minor stroke, and major stroke, were identified by face-to-face follow-up. A multivariate, ordinal, logistic regression model was used to determine significant predictors of recurrent events. RESULTS: Of 106 TIA patients, 24 (22.6%) had recurrent TIA and 20 (18.9%) had a stroke within 7 days. Hypertension, dyslipidemia, a history of ischemic stroke or TIA, and ABCD(2) score were significantly associated with the recurrent events after TIA (P<0.001, P=0.02, P<0.001, P=0.02). Hypertension (RR=9.21; 95% CI, 3.07–27.61, P<0.001) and duration of symptom (RR=1.10; 95% CI, 1.02–1.17, P=0.01) as an item of ABCD(2) score were highly predictive of the severity of recurrent events, whereas ABCD(2) score as a whole (P=0.18) proved to be less strongly predictive. CONCLUSIONS: A history of hypertension and long duration of symptom independently and significantly predict severe recurrent events after TIA within 7 days, but a high ABCD(2) score was less strongly predictive of severe recurrent events. International Scientific Literature, Inc. 2015-01-21 /pmc/articles/PMC4310715/ /pubmed/25604068 http://dx.doi.org/10.12659/MSM.892525 Text en © Med Sci Monit, 2015 This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License
spellingShingle Clinical Research
Li, Qiang
Zhu, Xiaolong
Feng, Chao
Fang, Min
Liu, Xueyuan
Duration of Symptom and ABCD(2) Score as Predictors of Risk of Early Recurrent Events after Transient Ischemic Attack: A Hospital-Based Case Series Study
title Duration of Symptom and ABCD(2) Score as Predictors of Risk of Early Recurrent Events after Transient Ischemic Attack: A Hospital-Based Case Series Study
title_full Duration of Symptom and ABCD(2) Score as Predictors of Risk of Early Recurrent Events after Transient Ischemic Attack: A Hospital-Based Case Series Study
title_fullStr Duration of Symptom and ABCD(2) Score as Predictors of Risk of Early Recurrent Events after Transient Ischemic Attack: A Hospital-Based Case Series Study
title_full_unstemmed Duration of Symptom and ABCD(2) Score as Predictors of Risk of Early Recurrent Events after Transient Ischemic Attack: A Hospital-Based Case Series Study
title_short Duration of Symptom and ABCD(2) Score as Predictors of Risk of Early Recurrent Events after Transient Ischemic Attack: A Hospital-Based Case Series Study
title_sort duration of symptom and abcd(2) score as predictors of risk of early recurrent events after transient ischemic attack: a hospital-based case series study
topic Clinical Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310715/
https://www.ncbi.nlm.nih.gov/pubmed/25604068
http://dx.doi.org/10.12659/MSM.892525
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