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Macrophages phagocytose nonopsonized silica particles using a unique microtubule-dependent pathway
Silica inhalation leads to the development of the chronic lung disease silicosis. Macrophages are killed by uptake of nonopsonized silica particles, and this is believed to play a critical role in the etiology of silicosis. However, the mechanism of nonopsonized-particle uptake is not well understoo...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The American Society for Cell Biology
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310742/ https://www.ncbi.nlm.nih.gov/pubmed/25428990 http://dx.doi.org/10.1091/mbc.E14-08-1301 |