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The influence of aerobic fitness status on ventilatory efficiency in patients with coronary artery disease

OBJECTIVE: To test the hypotheses that 1) coronary artery disease patients with lower aerobic fitness exhibit a lower ventilatory efficiency and 2) coronary artery disease patients with lower initial aerobic fitness exhibit greater improvements in ventilatory efficiency with aerobic exercise trainin...

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Autores principales: Prado, Danilo M L, Rocco, Enéas A, Silva, Alexandre G, Silva, Priscila F, Lazzari, Jaqueline M, Assumpção, Gabriela L, Thies, Sheyla B, Suzaki, Claudia Y, Puig, Raphael S, Furlan, Valter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4311117/
https://www.ncbi.nlm.nih.gov/pubmed/25672429
http://dx.doi.org/10.6061/clinics/2015(01)09
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author Prado, Danilo M L
Rocco, Enéas A
Silva, Alexandre G
Silva, Priscila F
Lazzari, Jaqueline M
Assumpção, Gabriela L
Thies, Sheyla B
Suzaki, Claudia Y
Puig, Raphael S
Furlan, Valter
author_facet Prado, Danilo M L
Rocco, Enéas A
Silva, Alexandre G
Silva, Priscila F
Lazzari, Jaqueline M
Assumpção, Gabriela L
Thies, Sheyla B
Suzaki, Claudia Y
Puig, Raphael S
Furlan, Valter
author_sort Prado, Danilo M L
collection PubMed
description OBJECTIVE: To test the hypotheses that 1) coronary artery disease patients with lower aerobic fitness exhibit a lower ventilatory efficiency and 2) coronary artery disease patients with lower initial aerobic fitness exhibit greater improvements in ventilatory efficiency with aerobic exercise training. METHOD: A total of 123 patients (61.0±0.7 years) with coronary artery disease were divided according to aerobic fitness status into 3 groups: group 1 (n = 34, peak VO(2)<17.5 ml/kg/min), group 2 (n = 67, peak VO(2)>17.5 and <24.5 ml/kg/min) and group 3 (n = 22, peak VO(2)>24.5 ml/kg/min). All patients performed a cardiorespiratory exercise test on a treadmill. Ventilatory efficiency was determined by the lowest VE/VCO(2) ratio observed. The exercise training program comprised moderate-intensity aerobic exercise performed 3 times per week for 3 months. Clinicaltrials.gov: NCT02106533 RESULTS: Before intervention, group 1 exhibited both lower peak VO(2) and lower ventilatory efficiency compared with the other 2 groups (p<0.05). After the exercise training program, group 1 exhibited greater improvements in aerobic fitness and ventilatory efficiency compared with the 2 other groups (group 1: ▵ = -2.5±0.5 units; group 2: ▵ = -0.8±0.3 units; and group 3: ▵ = -1.4±0.6 units, respectively; p<0.05). CONCLUSIONS: Coronary artery disease patients with lower aerobic fitness status exhibited lower ventilatory efficiency during a graded exercise test. In addition, after 3 months of aerobic exercise training, only the patients with initially lower levels of aerobic fitness exhibited greater improvements in ventilatory efficiency.
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spelling pubmed-43111172015-02-09 The influence of aerobic fitness status on ventilatory efficiency in patients with coronary artery disease Prado, Danilo M L Rocco, Enéas A Silva, Alexandre G Silva, Priscila F Lazzari, Jaqueline M Assumpção, Gabriela L Thies, Sheyla B Suzaki, Claudia Y Puig, Raphael S Furlan, Valter Clinics (Sao Paulo) Clinical Science OBJECTIVE: To test the hypotheses that 1) coronary artery disease patients with lower aerobic fitness exhibit a lower ventilatory efficiency and 2) coronary artery disease patients with lower initial aerobic fitness exhibit greater improvements in ventilatory efficiency with aerobic exercise training. METHOD: A total of 123 patients (61.0±0.7 years) with coronary artery disease were divided according to aerobic fitness status into 3 groups: group 1 (n = 34, peak VO(2)<17.5 ml/kg/min), group 2 (n = 67, peak VO(2)>17.5 and <24.5 ml/kg/min) and group 3 (n = 22, peak VO(2)>24.5 ml/kg/min). All patients performed a cardiorespiratory exercise test on a treadmill. Ventilatory efficiency was determined by the lowest VE/VCO(2) ratio observed. The exercise training program comprised moderate-intensity aerobic exercise performed 3 times per week for 3 months. Clinicaltrials.gov: NCT02106533 RESULTS: Before intervention, group 1 exhibited both lower peak VO(2) and lower ventilatory efficiency compared with the other 2 groups (p<0.05). After the exercise training program, group 1 exhibited greater improvements in aerobic fitness and ventilatory efficiency compared with the 2 other groups (group 1: ▵ = -2.5±0.5 units; group 2: ▵ = -0.8±0.3 units; and group 3: ▵ = -1.4±0.6 units, respectively; p<0.05). CONCLUSIONS: Coronary artery disease patients with lower aerobic fitness status exhibited lower ventilatory efficiency during a graded exercise test. In addition, after 3 months of aerobic exercise training, only the patients with initially lower levels of aerobic fitness exhibited greater improvements in ventilatory efficiency. Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo 2015-01 /pmc/articles/PMC4311117/ /pubmed/25672429 http://dx.doi.org/10.6061/clinics/2015(01)09 Text en Copyright © 2015 Hospital das Clínicas da FMUSP http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Science
Prado, Danilo M L
Rocco, Enéas A
Silva, Alexandre G
Silva, Priscila F
Lazzari, Jaqueline M
Assumpção, Gabriela L
Thies, Sheyla B
Suzaki, Claudia Y
Puig, Raphael S
Furlan, Valter
The influence of aerobic fitness status on ventilatory efficiency in patients with coronary artery disease
title The influence of aerobic fitness status on ventilatory efficiency in patients with coronary artery disease
title_full The influence of aerobic fitness status on ventilatory efficiency in patients with coronary artery disease
title_fullStr The influence of aerobic fitness status on ventilatory efficiency in patients with coronary artery disease
title_full_unstemmed The influence of aerobic fitness status on ventilatory efficiency in patients with coronary artery disease
title_short The influence of aerobic fitness status on ventilatory efficiency in patients with coronary artery disease
title_sort influence of aerobic fitness status on ventilatory efficiency in patients with coronary artery disease
topic Clinical Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4311117/
https://www.ncbi.nlm.nih.gov/pubmed/25672429
http://dx.doi.org/10.6061/clinics/2015(01)09
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