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A non-mitotic role for Aurora kinase A as a direct activator of cell migration upon interaction with PLD, FAK and Src
Timely activation of Aurora kinase A (AURA, also known as AURKA) is vital for centrosome formation and the progression of mitosis. Nonetheless, it is still unclear if and when other cellular functions are activated by AURA. We report here that Src phosphorylates and activates AURA at T288, and AURA...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4311130/ https://www.ncbi.nlm.nih.gov/pubmed/25501815 http://dx.doi.org/10.1242/jcs.157339 |