Comparative risk assessment of alcohol, tobacco, cannabis and other illicit drugs using the margin of exposure approach

A comparative risk assessment of drugs including alcohol and tobacco using the margin of exposure (MOE) approach was conducted. The MOE is defined as ratio between toxicological threshold (benchmark dose) and estimated human intake. Median lethal dose values from animal experiments were used to deri...

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Detalles Bibliográficos
Autores principales: Lachenmeier, Dirk W., Rehm, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4311234/
https://www.ncbi.nlm.nih.gov/pubmed/25634572
http://dx.doi.org/10.1038/srep08126

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4311234/
https://www.ncbi.nlm.nih.gov/pubmed/25634572
http://dx.doi.org/10.1038/srep08126

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