Optimized tuning of TALEN specificity using non-conventional RVDs

A key feature when designing DNA targeting tools and especially nucleases is specificity. The ability to control and tune this important parameter represents an invaluable advance to the development of such molecular scissors. Here, we identified and characterized new non-conventional RVDs (ncRVDs)...

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Detalles Bibliográficos
Autores principales: Juillerat, Alexandre, Pessereau, Coline, Dubois, Gwendoline, Guyot, Valérie, Maréchal, Alan, Valton, Julien, Daboussi, Fayza, Poirot, Laurent, Duclert, Aymeric, Duchateau, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4311247/
https://www.ncbi.nlm.nih.gov/pubmed/25632877
http://dx.doi.org/10.1038/srep08150

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