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Relationship between promoter methylation & tissue expression of MGMT gene in ovarian cancer

BACKGROUND & OBJECTIVES: Epigenetic alterations, in addition to multiple gene abnormalities, are involved in the genesis and progression of human cancers. Aberrant methylation of CpG islands within promoter regions is associated with transcriptional inactivation of various tumour suppressor gene...

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Detalles Bibliográficos
Autores principales:	Shilpa, V., Bhagat, Rahul, Premalata, C.S., Pallavi, V.R., Ramesh, G., Krishnamoorthy, Lakshmi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Medknow Publications & Media Pvt Ltd 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4311314/ https://www.ncbi.nlm.nih.gov/pubmed/25579142

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